Real‐World Glycemic Outcomes of Open‐Source Automated Insulin Delivery During 12 Months Among People With Type 1 Diabetes Across Age Groups
Authors' conclusion
Open-source AAPS achieved sustained glycemic improvement across age groups in T1D people.
Study context
- Population
- People with T1D who had used open-source android artificial pancreas (AAPS) continuously for 12 months; median age 26.1 (11.9, 36.7) years, T1D duration 2.1 (0.2, 8.4) years
- Participants
- 190 people
- Exposure
- Open-source AAPS use across age groups
- Outcome
- Glycemic outcomes (TIR 70-180 mg/dL, TBR <70 mg/dL) by age group
- Follow-up
- 3, 6 and 12 months
Methodological detailsage-stratified, 12-month follow-up
- Age-stratified
- 12-month follow-up
Main finding
As reported in the abstract
Glycemic outcomes, whole cohort
- Mean TIR at 3 months
- 79.9% ± 11.8%
- Mean TIR at 6 months
- 77.8% ± 13.9%
- Mean TIR at 12 months
- 77.2% ± 13.5%
- TBR70 at 3 months
- 3.8 (1.9, 6.1)%
- TBR70 at 6 months
- 3.3 (1.6, 5.8)%
- TBR70 at 12 months
- 3.6 (2.0, 6.6)%
Observational data: associations, not effects.
Further findings
TBR70 by age group · 12 months
Factors associated with composite target (TIR >70% and TBR70 <4%) at 12 months
| OR | P value | |
|---|---|---|
| Longer time in automation (adults)Exploratory analyses | 1.04 | P = 0.03 |
| Higher meal announcement frequency (paediatrics under 18 years)Exploratory analyses | 1.35 | P < 0.01 |
Mean
| Outcome | 13-18 years | > 45 years |
|---|---|---|
| TIR by age group · 12 monthsOther age groups not reported in abstract | 72.8% (SD 15.5%) | 78.9% (SD 11.8%) |
TBR70 by age group · 12 months
- > 45 years had relatively less hypoglycemia
Original publication
Real‐World Glycemic Outcomes of Open‐Source Automated Insulin Delivery During 12 Months Among People With Type 1 Diabetes Across Age Groups. Diabetes Obes Metab. Published 27 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →