Radiofrequency ablation for thyroid Bethesda III nodules: preliminary results
Authors' conclusion
RFA may be another safe alternative except for active surveillance or surgical excision for AUS/FLUS nodules with low-suspicion Thyroid Imaging Reporting and Data System features for patients who are unsuitable or strongly refuse surgery. Long-term results remain uncertain, thus further follow-up study is necessary.
Study context
- Population
- Adults with initial Bethesda III (AUS/FLUS) thyroid nodules; Bethesda IV or V on second aspiration excluded; mean age 47.6 years, 82.1% female30 nodules
- Participants
- 28 adults
- Outcome
- Feasibility of RFA: nodule volume reduction rate (VRR) and complications
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- Mean nodule volume pre-RFA
- 7.92 mL
- Mean nodule volume at 6 months
- 2.42 mL
- Mean nodule volume at 12 months
- 1.25 mL
- Volume reduction rate (VRR) at 6 months
- 77.9%
- VRR at 12 months
- 87.4%
Observational data: associations, not effects.
Safety
- Patients with post-RFA complications
- 2
- Transient vocal cord palsy
- 1
- Isthmus minor rupture
- 1
Original publication
Radiofrequency ablation for thyroid Bethesda III nodules: preliminary results. Eur Thyroid J. Published 9 October 2023. doi:10.
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