Psoriasis and risk of diabetic retinopathy in patients with type 2 diabetes mellitus
Main finding · DRResult — go to the resultHazard ratio 2.111 95 % CI 1.871–2.383Authors' conclusion
Psoriasis is associated with an increased risk of DR in patients with T2DM, highlighting the need for heightened clinical vigilance regarding DR in patients with T2DM and psoriasis.
Study context
- Population
- Patients with T2D with or without prior psoriasis diagnosis, TriNetX databasematched cohort
- Exposure
- T2D with psoriasis vs T2D without psoriasis
- Outcome
- Risk of diabetic retinopathy (DR)
Methodological detailspropensity-score matched, TriNetX database
- Propensity-score matched
- TriNetX database
Main finding
DR
Hazard ratio
2.111
95 % CI 1.871–2.383
Psoriasisvs Without psoriasis
HR 2.111 (95 % CI 1.871–2.383)
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
| Outcome | HR (95 % CI) | |
|---|---|---|
| Vision-threatening DRPsoriasisvs Without psoriasis | 2.424 (1.937–3.034) | |
| Non-proliferative DRPsoriasisvs Without psoriasis | 2.152 (1.854–2.497) | |
| Mild NPDRPsoriasisvs Without psoriasis | 2.082 (1.765–2.457) | |
| Moderate NPDRPsoriasisvs Without psoriasis | 2.848 (2.000–4.056) | |
| Proliferative DRPsoriasisvs Without psoriasis | 2.622 (1.753–3.922) | |
| DMEPsoriasisvs Without psoriasis | 2.312 (1.794–2.981) | |
| 0.20.5125Hazard ratio (log scale) |
Severe non-proliferative DR (NPDR)
- No higher risk of severe NPDR with psoriasis
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Psoriasis and risk of diabetic retinopathy in patients with type 2 diabetes mellitus. Diabetes Res Clin Pract. Published 18 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →