Prospective association of daily ambulatory activity with metabolic syndrome in middle-aged and older Japanese adults: the Toon Health Study
Authors' conclusion
Among the variables related to AA, the index of daily amount AA, in particular, may be linked to the onset of MetS.
Study context
- Population
- Middle-aged and older Japanese adults initially free from metabolic syndrome (MetS) (women 76.8%; mean age 56.9 years); Ambulatory activity (AA) measured by uniaxial accelerometer at baseline
- Participants
- 1,034 participants
- Exposure
- Quartiles of daily ambulatory activity: third vs first quartile
- Outcome
- Onset of MetS (Japanese diagnostic criteria)
- Follow-up
- 5-year follow-up
Main finding
As reported in the abstract
MetS onset
Estimate (95% CI)
Q3vs Q1
multivariate adjusted OR (number of steps) 0.386(0.197–0.755)
Q3vs Q1
multivariate adjusted OR (LIAA) 0.527(0.285–0.975)
Q3vs Q1
multivariate adjusted OR (total AA) 0.392(0.206–0.745)
- Developed MetS (all participants)
- 116 (11.2%)
Observational data: associations, not effects.
Further findings
Restricted cubic spline: L-shaped association with MetS
- Number of steps, p for nonlinearity
- 0.066
- LIAA, p for nonlinearity
- 0.034
- Total AA, p for nonlinearity
- 0.040
Original publication
Prospective association of daily ambulatory activity with metabolic syndrome in middle-aged and older Japanese adults: the Toon Health Study. Int J Obes (Lond). Published 2 February 2024. doi:10.
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