Prognostic value of the Glucose-to-Albumin ratio in sepsis-related mortality: A retrospective ICU study
Authors' conclusion
GAR is a strong predictor of 30-day and 90-day mortality in septic ICU patients. Incorporating GAR into clinical risk models could improve decision-making and sepsis management.
Study context
- Population
- Septic ICU patients
- Exposure
- Glucose-to-albumin ratio (GAR) quartiles; GAR as continuous predictor of mortality
- Outcome
- 30-day and 90-day mortality
- Follow-up
- 30 and 90 days
Methodological detailsICU
- ICU
Main finding
As reported in the abstract
Mortality by GAR (Cox regression)
GAR independently associated with 30-day mortality, HR
1.071 (1.063-1.078), p < 0.001 (95% CI)
GAR independently associated with 90-day mortality, HR
1.071 (1.064-1.078), p < 0.001 (95% CI)
Quartile 4 had the lowest survival probability
log-rank p < 0.0001
Observational data: associations, not effects.
Further findings
Predictive performance (ROC)
- GAR AUC for 30-day mortality (highest among individual predictors)
- 0.66
- GAR AUC for 90-day mortality (highest among individual predictors)
- 0.65
- Stacked model AUC
- 0.826
RCS analysis
- L-shaped relationship between GAR and mortality
Original publication
Prognostic value of the Glucose-to-Albumin ratio in sepsis-related mortality: A retrospective ICU study. Diabetes Res Clin Pract. Published 7 May 2025. doi:10.
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