Prognostic role of sarcopenia in heart failure patients
An erratum to this article was published (Cardiovasc Diabetol, 28 Feb 2026 ↗)
Authors' conclusion
Patients with chronic HF that suffered from sarcopenia show a higher risk of MACE and total mortality, independently by their chronological age.
Study context
- Population
- Outpatients with chronic heart failure (HF)
- Participants
- 670 outpatients
- Exposure
- Sarcopenia vs no sarcopenia
- Sarcopenicn = 340
- Not sarcopenicn = 330reference
- Outcome
- MACE:
- Non-fatal ischemic stroke
- Non-fatal MI
- Cardiac revascularization or coronary bypass surgery
- CV death
- Follow-up
- Mean 4.7 years
Main finding
As reported in the abstract
MACE
Sarcopenic
13.3 events/100 patient-year
Not sarcopenic
2.1 events/100 patient-year
P < 0.001
- Multivariate analysis: sarcopenia increased major adverse cardiac events (MACE) risk by a factor of
- 8.6
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| Total mortalityHigher incidence with sarcopenia | P < 0.001 |
Original publication
Prognostic role of sarcopenia in heart failure patients. Cardiovasc Diabetol. Published 28 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →