Prognostic Analysis of 131I Efficacy After Papillary Thyroid Carcinoma Surgery Based on Computed Tomography (CT) Radiomics
An erratum to this article was published (J Clin Endocrinol Metab, 18 Dec 2024 ↗)
Authors' conclusion
The preoperative CT-based radiomics model can effectively predict the efficacy of initial postoperative 131I treatment in patients with intermediate- or high-risk PTC, and the radiomics-clinical combined model exhibits better predictive performance.
Study context
- Population
- Patients with PTC who received total thyroidectomy and initial 131I treatment
- Participants
- 181 patients
- Comparison
- Clinical model vs CT radiomics model vs radiomics-clinical combined model
- Outcome
- Prediction of efficacy of initial postoperative 131I treatment (AUC, sensitivity, specificity)
Methodological detailsradiomics, training and testing sets (7:3 ratio)
- Radiomics
- Training and testing sets (7:3 ratio)
Performance
As reported in the abstract
Prediction of efficacy of initial 131I treatment
| Test or model | AUC | Sensitivity | Specificity |
|---|---|---|---|
| Clinical model | 0.895 | 0.899 | 0.816 |
| Radiomics model (training set) | 0.825 | 0.828 | 0.745 |
| Radiomics model (testing set) | 0.809 | 0.636 | 0.944 |
AUC
Clinical model0.895
Radiomics model (training set)0.825
Radiomics model (testing set)0.809
Sensitivity
Clinical model0.899
Radiomics model (training set)0.828
Radiomics model (testing set)0.636
Specificity
Clinical model0.816
Radiomics model (training set)0.745
Radiomics model (testing set)0.944
Further findings
Independent clinical risk factor for efficacy of initial 131I treatment
- Pre-131I treatment serum Tg (multivariate analysis)
- P = 0.002
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Prognostic Analysis of 131I Efficacy After Papillary Thyroid Carcinoma Surgery Based on CT Radiomics. J Clin Endocrinol Metab. Published 27 May 2024. doi:10.
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