Osteoporosis, bone & mineral

Primary hyperparathyroidism in adults—(Part II) surgical management and postoperative follow‐up: Position statement of the Endocrine Society of Australia, The Australian & New Zealand Endocrine Surgeons, and The Australian & New Zealand Bone and Mineral Society

Clin Endocrinol (Oxf)Published Position statement

Methodological detailsADAPTE guideline adaptation, systematic approach, eight key questions
  • ADAPTE guideline adaptation
  • Systematic approach
  • Eight key questions

Recommendations

As issued by the authors

  1. Diagnostic imaging does not determine suitability for surgery but can guide surgical planning in suitable candidates

  2. First-line imaging: US and either parathyroid 4DCT or scintigraphy, depending on local availability and expertise

  3. Minimally invasive parathyroidectomy is appropriate in most patients with concordant imaging

  4. Consider bilateral neck exploration with discordant/negative imaging, multi-gland disease and genetic/familial risk factors

  5. Parathyroid surgery, especially re-operative, has better outcomes with higher volume surgeons

  6. Neuromonitoring generally not required for initial surgery but should be considered for re-operative surgery

  7. After parathyroidectomy, re-check calcium and PTH in the first 24 h; repeat early if risk factors for hypocalcaemia

  8. Eucalcaemia at 6 months is consistent with surgical cure; PTH need not be re-checked absent other clinical indications

  9. Longer-term surveillance of skeletal health is recommended

Original publication

Primary hyperparathyroidism in adults—(Part II) surgical management and postoperative follow‐up: Position statement of the Endocrine Society of Australia, The Australian & New Zealand Endocrine Surgeons, and The Australian & New Zealand Bone and Mineral Society. Clin Endocrinol (Oxf). Published 19 December 2021. doi:10.1111/cen.14650

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