Obesity

Prevalence of Pre‐Clinical Obesity Among US Adults Receiving Medical and Surgical Obesity Treatment

Obesity (Silver Spring)Published Retrospective cohort study

Authors' conclusion

This novel framework would reclassify a significant proportion of patients as having pre-clinical obesity.

Study context

Population
US adults with BMI ≥ 35 who received bariatric surgery (BS) or antiobesity medications (AOMs), 2017–2023, ≥ 6-month continuous enrollment before treatment
Exposure
Clinical obesity vs pre-clinical obesity
Outcome
Proportion classified as pre-clinical vs clinical obesity
Methodological detailsMerative MarketScan database, multivariable logistic regression
  • Merative MarketScan database
  • Multivariable logistic regression

Main finding

As reported in the abstract

Prevalence of pre-clinical obesity

Observational data: associations, not effects.

Further findings

Characteristics

Clinical obesity patients were older with a higher comorbidity burden vs pre-clinical obesity

Safety

OutcomeaORP value
Treatment-related complications · within 90 days of treatment initiationClinical obesity vs Pre-clinical obesity · AOM1.10P < 0.001
Treatment-related complications · within 90 days of treatment initiationClinical obesity vs Pre-clinical obesity · BS1.39P < 0.001

Original publication

Prevalence of Pre‐Clinical Obesity Among US Adults Receiving Medical and Surgical Obesity Treatment. Obesity (Silver Spring). Published 20 May 2026. doi:10.1002/oby.70171

Composed by AI from the published abstract and checked against it. How Briefs are made →

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