Prevalence and Description of the Skin Reactions Associated with Adhesives in Diabetes Technology Devices in an Adult Population: Results of the CUTADIAB Study
Authors' conclusion
Skin reactions were common, with similar presentations in CGM and CSII users. Manifestations suggested skin irritation rather than allergies. These reactions rarely led to the definitive discontinuation of the use of the device.
Study context
- Population
- Adults with diabetes seen in consultation over 7 months, using or having used a device with skin adhesives (in the last 10 years)
- Participants
- 851 adults
- Exposure
- Continuous glucose monitoring (CGM) vs continuous subcutaneous insulin infusion (CSII) users
- Outcome
- Prevalence and consequences of skin reactions at CGM or CSII sites
Methodological detailsmulticenter, self-assessment questionnaire
- Multicenter
- Self-assessment questionnaire
Main finding
As reported in the abstract
Skin reaction reported
Observational data: associations, not effects.
Further findings
Onset of manifestations among patients with reactions
Onset after >6 months
- Onset of manifestations among patients with reactions — Onset within first 24 h of first use (CGM and CSII)
- 22%-24%
Characteristics of patients reporting reactions
- Reactions more frequent in women using CGM and CSII; CGM users with reactions had T1D more often than T2D
- P < 0.001
Manifestations among patients with reactions (similar for CGM and CSII)
- Redness and pruritus
- 70%-75%
- Pain
- 20%-25%
- Vesicles and desquamation
- 12%-15%
Safety
Definitive discontinuation of device use · % of patients with reactions
Of all users
Original publication
Prevalence and Description of the Skin Reactions Associated with Adhesives in Diabetes Technology Devices in an Adult Population: Results of the CUTADIAB Study. Diabetes Technol Ther. Published 24 February 2023. doi:10.
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