Type 2 & other diabetes

Prevalence and incidence of heart failure in type 2 diabetes patients: results from a nationwide prospective cohort—the DIABET-IC study

Cardiovasc DiabetolPublished Prospective cohort study

Authors' conclusion

In this contemporary cohort of T2D patients attending cardiology and endocrinology outpatient clinics, the prevalence and incidence of HF were high, comorbidities were frequent, and the use of antidiabetic agents with cardiovascular benefit was low. Outpatient care seems to be a unique opportunity for a comprehensive T2D approach that encompasses HF prevention, diagnosis, and treatment.

Study context

Population
Patients with T2D attending cardiology and endocrinology outpatient clinics in 30 centres in Spain, 2018–2019; 67.6 ± 10.1 years, 31.7% female
Participants
1,249 patients
Outcome
Prevalence of HF at baseline and incidence of HF
Follow-up
3 year
Methodological detailsobservational, multicentre, nationwide
  • Observational
  • Multicentre
  • Nationwide

Main finding

As reported in the abstract

HF prevalence and incidence

Heart failure (HF) at baseline (prevalence)

490 participants

39.2%

Preserved ejection fraction among baseline HF

150

30.6%

New HF diagnoses among those without baseline HF (incidence)

58

7.6%

Incidence rate

3.0 per 100 person-years

Observational data: associations, not effects.

Further findings

Characteristics of HF patients

Adverse social determinants and chronic conditions (CKD, atherosclerotic CVD) more frequent in HF patients

Independent predictors of incident HF

Smoking, LVEF, NT-ProBNP, history of tachyarrhythmia, and treatment with pioglitazone, oral anticoagulants or diuretics

Use of antidiabetic drugs with cardiovascular benefits

SGLT2i use
30.4%
GLP-1 RA use
12.5%
  • Despite an average suboptimal glycaemic control

Original publication

Prevalence and incidence of heart failure in type 2 diabetes patients: results from a nationwide prospective cohort—the DIABET-IC study. Cardiovasc Diabetol. Published 16 July 2024. doi:10.1186/s12933-024-02358-0

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