Preoperative MRI bone texture is associated with complications after spine fusion
Authors' conclusion
In summary, greater heterogeneity of pre-operative bone texture from clinical MRIs was associated with skeletal complications following spine fusion.
Study context
- Population
- Patients undergoing instrumented lumbar spine fusion; mean age 63 years, 54% femaleenrolled
- Participants
- 72 patients
- Exposure
- Pre-operative MRI bone texture and DXA areal BMD (aBMD) in patients with vs without post-operative skeletal complications
- Complicationsn = 27
- Outcome
- Post-operative skeletal complications in relation to pre-operative MRI texture (L1-L5) and aBMD by DXA
- Follow-up
- Median 13 months
Main finding
As reported in the abstract
Pre-operative MRI texture features, complications vs no complications
- Complications
- difference in contrast 26%; P < 0.01 for all
- Complications
- difference in entropy 12%; P < 0.01 for all
- Complications
- difference in angular second moment (ASM) −13%; P < 0.01 for all
- Complications
- difference in inverse difference moment (IDM) −25%; P < 0.01 for all
Observational data: associations, not effects.
Safety
Post-operative skeletal complications · median 13 months
- Skeletal complications
- 27 patients (38%)
- Most common: proximal junctional kyphosis and screw loosening
Original publication
Preoperative MRI bone texture is associated with complications after spine fusion. J Bone Miner Res. Published 26 March 2026. doi:10. 1093/ jbmr/ zjag060
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