Obesity

Prenatal interventions and the development of childhood obesity

Pediatr ObesPublished Systematic review of follow-up studies of prenatal randomised controlled trials

Authors' conclusion

No strong association was found between prenatal diet, exercise, or combined interventions and child adiposity. Data are limited due to 63.6% overall retention rate for the follow-up studies and heterogeneity of intervention approach and child adiposity measures. Findings suggest combined interventions initiated early in pregnancy may decrease offspring adiposity in the first year of life.

Study context

Population
Offspring of completed prenatal RCTs with adiposity-related outcomes assessed beyond birth
Participants
4,277 offspring18 follow-up studies
Comparison
Prenatal diet, exercise or combined interventions
Outcome
Child adiposity (anthropometrics; body composition in 15 studies)
Follow-up
Beyond birth

Pooled result

As reported in the abstract

Child adiposity
  • Diet or exercise interventions had no consistent significant effect on child adiposity
  • Three combined interventions resulted in lower child adiposity at 3, 6 and 12 months

Further pooled results

Retention in follow-up studies

Overall retention rate
63.6%

Original publication

Prenatal interventions and the development of childhood obesity. Pediatr Obes. Published 14 September 2022. doi:10.1111/ijpo.12981

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