Preferences for basal insulin treatments in adults with type 2 diabetes: A discrete choice experiment in France and Spain
Authors' conclusion
This study highlights the importance of administration frequency in basal insulin treatment decisions when glycemic control is held constant. Participants indicated a preference for OW injection frequency, suggesting fewer injections may reduce the burden of insulin administration. These insights support clinical consideration of less frequent injections when making T2D treatment decisions.
Study context
- Population
- Adults with T2D in France and Spain; basal insulin and GLP-1 RA naïve, basal insulin naïve but GLP-1 RA experienced, basal insulin experiencedcompleted survey · GLP-1 RA naïve 86 · basal insulin experienced 68
- Participants
- 239 adults
- Comparison
- Preferences across basal insulin treatment attributes, incl. frequency of administration (once weekly (OW) vs once daily (OD) vs BD)
- Francen = 166
- Spainn = 73
- Outcome
- Relative importance of frequency of administration in basal insulin treatment preferences
Methodological detailstargeted literature review and qualitative interviews informing attributes, pilot interviews, hierarchical Bayesian estimation, France and Spain
- Targeted literature review and qualitative interviews informing attributes
- Pilot interviews
- Hierarchical Bayesian estimation
- France and Spain
Main finding
As reported in the abstract
Relative importance of frequency of administration
39%
Relative importance of next highest attribute, risk of severe hypoglycaemic event (insulin experienced rates)
21%
Further findings
Most positive impacts of OW administration
- Reduction in frequency of missing doses and taking doses at prescribed time considered most positive impacts of OW
Treatment experience subgroups
- Findings consistent across treatment experience groups
Original publication
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