Predictors of readmission and mortality in adults with diabetes or stress hyperglycemia after initial hospitalization for COVID-19
Authors' conclusion
Understanding predictors of readmission after initial hospitalization for COVID-19, including older age, lower eGFR, comorbidities, ICU admission, mechanical ventilation, statin use and DKA but not HbA1c, glycemic gap or BMI, can help guide treatment approaches and future research in adults with diabetes.
Study context
- Population
- Adults with diabetes or stress hyperglycemia (glucose>180 mg/dL twice in 24 hours) with hemoglobin A1c (HbA1c) on or within 3 months before initial admission with COVID-19, March 2020 to February 2021, five university hospitals1,502 alive after initial hospitalization
- Participants
- 1,786 adults
- Outcome
- Readmission after initial hospitalization for COVID-19
Methodological detailsmulticentre, five university hospitals, retrospective review of electronic medical records
- Multicentre
- Five university hospitals
- Retrospective review of electronic medical records
Main finding
As reported in the abstract
Readmission
Readmitted, of patients alive after initial hospitalization
19.4%
Readmissions within 30 days
90.3%
Time to readmission, median (IQR)
4 (0-14) days
Observational data: associations, not effects.
Further findings
Mortality during readmission
- Mortality during readmission
- 8.0% (n=23)
- Died vs survived: older, mean±SD age 74.9±9.5 vs 65.2±14.4 years
- P = 0.002
- Died more likely had diabetic ketoacidosis (DKA) during first hospitalization
- P < 0.001
Intensive care unit (ICU) stay during readmission
- Shorter length of stay (LOS) during initial admission associated with ICU stay during readmission
Original publication
Predictors of readmission and mortality in adults with diabetes or stress hyperglycemia after initial hospitalization for COVID-19. BMJ Open Diabetes Res Care. Published 27 June 2024. doi:10.
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