Type 1 diabetes

Prediction of Insulin Requirements by Explainable Machine Learning for Individuals With Type 1 Diabetes

J Clin Endocrinol MetabPublished Retrospective observational study

Authors' conclusion

We here developed machine-learning models that predict the TDD of insulin from clinical information. Such models could contribute to the treatment of many individuals undergoing insulin therapy, with further developments being warranted.

Study context

Population
Individuals with T1D using CGM with CSII, Kobe University Hospital, April 1, 2010 to February 29, 2024
Participants
110 individuals
Outcome
Performance of machine-learning models predicting total daily dose (TDD) of insulin, by mean absolute percentage error (MAPE)
Methodological detailssingle-centre, machine learning, explainable artificial intelligence
  • Single-centre
  • Machine learning
  • Explainable artificial intelligence

Main finding

As reported in the abstract

MAPE for TDD of insulin prediction
GroupValueMean absolute percentage error (MAPE)
Random forest19.8%19.8%

Random forest

Value19.8%
Mean absolute percentage error (MAPE)19.8%

Observational data: associations, not effects.

Original publication

Prediction of Insulin Requirements by Explainable Machine Learning for Individuals With Type 1 Diabetes. J Clin Endocrinol Metab. Published 11 December 2024. doi:10.1210/clinem/dgae863

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