Osteoporosis, bone & mineral

A prediction model of elderly hip fracture mortality including preoperative red cell distribution width constructed based on the random survival forest (RSF) and Cox risk ratio regression

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

An independent correlation between pre-RDW and 1-year mortality after surgery in elderly hip fracture can be used to predict mortality in elderly hip fracture patients and has predictive significance in anemia patients.

Study context

Population
Elderly patients who underwent hip fracture surgery
Participants
2,106 patients
Exposure
Non-anemia vs Anemia
Outcome
Mortality within 1 year after hip fracture surgery
Follow-up
1 year
Methodological detailsprediction model, random survival forest, Cox regression, internal and external validation, nomogram
  • Prediction model
  • Random survival forest
  • Cox regression
  • Internal and external validation
  • Nomogram

Main finding

As reported in the abstract

Independent risk factors for 1-year mortality

RSF selected important influencing factors

12

Independent risk factors for death within 1 year on Cox regression, including preoperative RDW (pre-RDW)

8

Observational data: associations, not effects.

Further findings

Pre-RDW and 1-year mortality by anemia status (stratified analysis)

Pre-RDW still independently associated with 1-year mortality in the non-anemia group, not in the anemia group
Model from total cohort validated in anemia patients with good clinical benefits

Original publication

A prediction model of elderly hip fracture mortality including preoperative red cell distribution width constructed based on the random survival forest (RSF) and Cox risk ratio regression. Osteoporos Int. Published 7 December 2023. doi:10.1007/s00198-023-06988-0

Composed by AI from the published abstract and checked against it. How Briefs are made →

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