Predicting the Path to Attrition: Multidomain Risk Assessment in Diabetic Foot Ulcer Offloading Randomized Controlled Trials
Authors' conclusion
Baseline clinical, functional, and psychosocial variables, integrated through risk-normalized radar visualization, may guide retention strategies.
Study context
- Population
- Participants with DFU in an offloading device randomized controlled trial (RCT)
- Participants
- 210 participants
- Comparison
- Removable vs Removable plus education vs Smart removable
- Primary endpoint
- Attrition (withdrawal or loss to follow-up) predicted by baseline wound, functional and psychosocial metrics
Methodological details12-week RCT, multivariable logistic regression
- 12-week RCT
- Multivariable logistic regression
Primary result
As reported in the abstract
Attrition
Withdrew or lost to follow-up
76
36%
Slower gait independently predicted attrition (OR)
1.16
Higher depressive symptoms independently predicted attrition (OR)
1.52
Discrimination of integrated smart boot metrics (AUC)
0.81
Original publication
Predicting the Path to Attrition: Multidomain Risk Assessment in Diabetic Foot Ulcer Offloading Randomized Controlled Trials. Diabetes Care. Published 7 July 2026. doi:10.
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