Precision and age-related changes of 3D-DXA reconstructions and FEA of the proximal femur in comparison to DXA
Authors' conclusion
3D-DXA and thereon based FEA may offer interesting insights into the densitometric and mechanical quality of the proximal femur.
Study context
- Population
- DXA scans of the proximal femur from two datasets, reconstructed with 3D-Shaper software
- Participants
- 2,427 DXA scans
- Comparison
- 3D-DXA and 3D-DXA-based FEA vs standard DXA
- Outcome
- Short- and long-term precision of thirty 3D-DXA-based parameters and femoral strength in fall and stance configurations, related to change rates by trend assessment interval (TAI)
Methodological detailstwo datasets, short- and long-term precision, nonlinear finite element analysis
- Two datasets
- Short- and long-term precision
- Nonlinear finite element analysis
Main finding
As reported in the abstract
Long-term precision errors
Total hip aBMD
1.6%
Total hip integral vBMD
2.0%
Strength in fall
7.5%
Further findings
Trend assessment interval (TAI)
- Total hip aBMD
- 5.5 years
- Total hip integral vBMD
- 4.6
- Strength
- 5.8
- Higher change rates for vBMD and strength compensated the larger precision errors, giving similar TAIs
Correlation of errors between processing steps
- Errors between processing steps were only weakly correlated
Relative local precision errors of cortical parameters
- Largest in the superior and anterior neck region and above the lesser trochanter
Original publication
Precision and age-related changes of 3D-DXA reconstructions and FEA of the proximal femur in comparison to DXA. J Bone Miner Res. Published 25 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →