Post-Menarcheal Growth Patterns in a Contemporary Cohort of Latino Girls
Authors' conclusion
In a national and updated dataset, we observed that girls grew until 4 years PM an average of 6.6 ± 2.5 cm, with greatest gain occurring in the first year PM (3.8 ± 1.5 cm). Age at menarche was associated with menarche growth patterns.
Study context
- Population
- Contemporary healthy Chilean girls followed yearly after menarche until 4 years post-menarcheal (PM), GOCS cohort364 measured at 4 years PM
- Participants
- 534 participants
- Exposure
- Post-menarcheal growth by age at menarche
- Outcome
- Post-menarcheal growth (height gain)
- Follow-up
- 4 years PM
Methodological detailsnested within the GOCS cohort, SuperImposition by Translation and Rotation (SITAR) model
- Nested within the GOCS cohort
- SITAR model
Main finding
As reported in the abstract
Expected height gained PM, complete study group
Expected height gained PM (mean ± SD)
6.6 ± 2.5 cm
Height gain after the first year PM, the largest gain
3.8 ± 1.5 cm
Observational data: associations, not effects.
Further findings
| Outcome | Menarche <11 years | Menarche >13 years | P value |
|---|---|---|---|
| Height gain by age at menarche · 4 years PMGreater gain with earlier menarche | 8.2 ± 3.2 cm | 4.4 ± 1.6 | P < 0.001 |
PM growth patterns (size, timing, intensity) by age at menarche
- Age at menarche significantly associated with all PM growth patterns; older age at menarche: taller, later, slower growth; associations maintained after BMI adjustment
- SITAR, BMI-adjusted: menarche after 13 years had slower growth, slightly earlier and with less intensity
Original publication
Post-Menarcheal Growth Patterns in a Contemporary Cohort of Latino Girls. Horm Res Paediatr. Published 31 January 2024. doi:10.
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