Physical function trajectory after wrist or lower arm fracture in postmenopausal women: results from the Women’s Health Initiative Study
Main finding · Declining physical functioningResult — go to the resultAdjusted odds ratio 1.33 95% CI 1.19–1.49Authors' conclusion
Women with lower arm or wrist fracture, particularly those aged 80 and older, were more likely to experience declines in physical functioning than women without such fractures, independent of baseline physical functioning level.
Study context
- Population
- Postmenopausal women in the Women's Health Initiative Study
- Participants
- 2,097 vs 20,970
- Comparison
- Women with vs without lower arm or wrist fracture
- Casesn = 2,097
- Controlsn = 20,970reference
- Outcome
- Declining physical functioning trajectory (RAND 36-item Short-Form Health Survey physical functioning subscale, assessed annually), reference stable or improving trajectory
- Follow-up
- 5 years
Methodological detailsprospective data, stratified by age
- Prospective data
- Stratified by age
Main finding
Declining physical functioning
Adjusted odds ratio
1.33
95% CI 1.19–1.49
By group
Casesvs Controls
aOR 1.33 (95% CI 1.19–1.49)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Declining physical functioning by age (subgroups), fracture vs no fracture · 5 years
- Age ≥ 80 years, aOR
- 1.56 (95% CI 1.29-1.88)
- Age 70-79 years, aOR
- 1.29 (95% CI 1.09-1.52)
- Age < 70 years, aOR
- 1.15 (95% CI 0.86-1.53)
- Interaction by age
- P for interaction = 0.06
- Reference group stable or improving physical functioning trajectory
Declining physical functioning by baseline physical functioning or physical activity level (subgroups)
- Associations between lower arm or wrist fracture and odds of declining physical functioning did not vary by baseline physical functioning or physical activity level
Original publication
Physical function trajectory after wrist or lower arm fracture in postmenopausal women: results from the Women’s Health Initiative Study. Osteoporos Int. Published 9 March 2024. doi:10.
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