Type 2 & other diabetes

Perioperative glycaemic profiles in Aboriginal and Torres Strait Islander people with diabetes mellitus

Diabet MedPublished Retrospective cohort study

Authors' conclusion

Despite being 14 years younger and having greater preoperative comorbidity and higher HbA1c levels, Aboriginal and Torres Strait Islander people demonstrated higher rates of perioperative hypoglycaemia, but otherwise broadly comparable perioperative glycaemic profiles to their non-Indigenous Australian counterparts. Further research should ideally be Indigenous-led, and prospectively evaluate interventions to both reduce cumulative glycaemic burden and optimise perioperative glycaemia using modern diabetes technologies in Aboriginal and Torres Strait Islander people both with and without diabetes mellitus.

Study context

Population
Adults with DM undergoing surgery in South Australia (2018–2023)
Participants
16,396 adults
Exposure
Aboriginal and Torres Strait Islander people vs non-Indigenous Australians
  • Aboriginal and Torres Strait Islander peoplen = 1,065
Outcome
Perioperative glycaemic profiles
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

  • Mean blood glucose levels (BGL), glycaemic variability and glycaemic ratios similar; higher hypoglycaemia in Aboriginal and Torres Strait Islander people, coinciding with greater inpatient use of sulphonylureas and insulin
  • Aboriginal and Torres Strait Islander people vs Non-Indigenous Australians: P = 0.032
  • Aboriginal and Torres Strait Islander people vs Non-Indigenous Australians: P = 0.045
  • Aboriginal and Torres Strait Islander people vs Non-Indigenous Australians: P = 0.382
  • Aboriginal and Torres Strait Islander people vs Non-Indigenous Australians: P < 0.001

Observational data: associations, not effects.

Further findings

Baseline characteristics

P < 0.001

Baseline characteristics

P < 0.001

Baseline characteristics

P < 0.001

OutcomeP value
Baseline characteristics54.3 vs. 68.2 years; youngerP < 0.001
Baseline characteristics68.5 mmol/L (8.4%) vs. 62.1 mmol/mol (7.8%); higherP < 0.001

Safety

Perioperative hypoglycaemia

P < 0.001

Original publication

Perioperative glycaemic profiles in Aboriginal and Torres Strait Islander people with diabetes mellitus. Diabet Med. Published 28 June 2026. doi:10.1111/dme.70400

Composed by AI from the published abstract and checked against it. How Briefs are made →

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