Patient-reported outcome measures (PROMs) are differently associated with treatment modalities, household income, and diabetes-related events in children with type 1 diabetes, their mothers, and their fathers: a French nationwide survey
Authors' conclusion
CL enhanced the QoL in families of children with T1D. Socioeconomic factors and diabetes-related events influence QoL differently depending on the respondent group.
Study context
- Population
- Children with T1D and their parents (mothers, fathers), French national family association Familles AJD, 2024; children aged 11.3 ± 4 years, diabetes duration 4.7 ± 3.8 years
- Participants
- 1,593 surveys
- Exposure
- Closed loop (CL) vs multiple daily injections (MDI), open loop (OL) and low glucose suspend (LGS)
- Outcome
- QoL in families (mothers, fathers and children)
Methodological detailsnationwide survey, population-based, multivariate analyses, Treatment use: 18% MDI, 41% OL, 13% LGS, 29% CL, Six validated questionnaires assessing quality of life (QoL), anxiety, time spent managing diabetes and sleep quality
- Nationwide survey
- Population-based
- Multivariate analyses
- Treatment use: 18% MDI, 41% OL, 13% LGS, 29% CL
- Six validated questionnaires assessing QoL, anxiety, time spent managing diabetes and sleep quality
Main finding
As reported in the abstract
QoL
- CL associated with improved QoL scores in parents (vs OL and MDI) and children (vs OL, not MDI)
- Multivariate analyses
Observational data: associations, not effects.
Further findings
| Outcome | CL | P value |
|---|---|---|
| HbA1cCL vs Other treatments | 7.3 ± 0.6 % | P < 0.05 |
- HbA1c: Other treatments 7.7 ± 1.0 %
Time spent managing diabetes
- Lower with CL in parents, not children
Anxiety and sleep quality
- Not improved with CL
Factors associated with QoL
- Child age (in parents) and household income (in all) associated with improved QoL
- HbA1c and history of DKA (in mothers), or history of severe hypoglycaemia (in children), had a deleterious effect
- Mothers had lower QoL, but scores correlated within the household
Original publication
Patient-reported outcome measures (PROMs) are differently associated with treatment modalities, household income, and diabetes-related events in children with type 1 diabetes, their mothers, and their fathers: a French nationwide survey. Diabetes Metab. Published 24 October 2025. doi:10.
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