Type 2 & other diabetes

Parental Income Level and Risk of Developing Type 2 Diabetes in Youth

JAMA Netw OpenPublished Retrospective cohort study

Authors' conclusion

This population-based cohort study showed that children and adolescents from very-low-income to middle-income families had a higher hazard of youth-onset type 2 diabetes and mortality than those from high-income families. Further research to reveal the factors underlying this association may improve the accuracy of identifying individuals at greatest risk for developing type 2 diabetes in youth.

Study context

Population
Children and adolescents aged 0 to 19 years, 2008 National Health Insurance Research Database of Taiwan, follow-up through December 31, 2019; mean (SD) age 11.2 (5.2) years, 48.3% girls
Participants
5,182,893 children
Exposure
Very-low-, low- and middle-income vs high-income families
Outcome
Youth-onset T2D
Follow-up
Mean (SD) 9.0 (0.3) years
Methodological detailsnationwide, population-based
  • Nationwide
  • Population-based

Main finding

As reported in the abstract

Very low income

0.52 cases per 1000 person-years

Low income

0.40 cases per 1000 person-years

Middle income

0.35 cases per 1000 person-years

High income

0.28 cases per 1000 person-years

Each group vs high incomeAdjusted hazard ratio (95% CI)
Very low income
1.55(1.41–1.71)
Low income
1.34(1.27–1.41)
Middle income
1.27(1.20–1.34)

Observational data: associations, not effects.

Further findings

OutcomeaHR (95% CI)
All-cause mortalityVery low incomevs High income2.18 (1.97–2.41)
All-cause mortalityLow incomevs High income1.51 (1.42–1.60)
All-cause mortalityMiddle incomevs High income1.22 (1.14–1.31)

Other risk factors for youth-onset T2D

Older age, female sex, obesity, dyslipidemia, gout or psychiatric disorders associated with significantly higher risk

Original publication

Parental Income Level and Risk of Developing Type 2 Diabetes in Youth. JAMA Netw Open. Published 1 November 2023. doi:10.1001/jamanetworkopen.2023.45812

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