Pancreatosteatosis in patients with adrenal incidentaloma: A risk factor for impaired glucose metabolism
Authors' conclusion
Our findings suggest that the presence of PS may provide significant information in predicting newly developed dysglycemia in patients with NFAI.
Study context
- Population
- Patients with non-functioning AI (NFAI) and controls matched for age, sex and BMI; Pancreatosteatosis (PS) assessed by non-contrast abdominal computed tomography (CT) at initial evaluationmatched controls
- Participants
- 80 vs 127
- Exposure
- NFAI vs controls; PS vs no PS within NFAI
- NFAIn = 80
- Controlsn = 127reference
- Outcome
- Changes in FPG and HbA1c
- Follow-up
- 2 years
Methodological detailscontrols matched for age, sex and BMI
- Controls matched for age, sex and BMI
Main finding
As reported in the abstract
Change in mean FPG
- Mean fasting plasma glucose (FPG) increased significantly after 2 years in both groups
- P < 0.001, for both
Observational data: associations, not effects.
Further findings
Increase in hemoglobin A1c (HbA1c) and FPG, PS vs no PS within NFAI · 2 years
- Increase in HbA1c significantly higher with PS than without PS
- P < 0.001
- Increase in FPG significantly higher with PS than without PS
- P = 0.00
Association of HbA1c change with PS in NFAI
- Change in HbA1c associated with presence of PS
- P < 0.001
Original publication
Pancreatosteatosis in patients with adrenal incidentaloma: A risk factor for impaired glucose metabolism. Diabetes Res Clin Pract. Published 20 January 2024. doi:10.
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