Overweight/obesity and gait abnormality: what role does the brain play in the relationship?
Authors' conclusion
Increased anthropometric indices are associated with relative prolongation of the stance phase and the iron levels of ITG mediates the associations.
Study context
- Population
- Community-dwelling older adults from the Taizhou Imaging Study
- Participants
- 710 adults
- Exposure
- Overweight/obesity vs normal weight
- Outcome
- Gait performance and cortical iron levels in overweight/obesity
Methodological detailscommunity-based, Taizhou Imaging Study
- Community-based
- Taizhou Imaging Study
Main finding
As reported in the abstract
- Phase domain (poorer performance), standardized β
- −0.172 (P = 0.023)
- Percentage of double support time, standardized β
- 0.783 (P = 0.028)
- Stance time, standardized β
- 0.422 (P = 0.019)
- Iron levels of inferior temporal gyrus (ITG), standardized β
- 0.641 (P = 0.021)
- ITG iron levels mediated association of BMI, waist circumference (WC), waist-to-height ratio, abdominal volume index and body roundness index with phase domain; mediation proportions
- 8.95% to 13.45%
Observational data: associations, not effects.
Original publication
Overweight/obesity and gait abnormality: what role does the brain play in the relationship? Int J Obes (Lond). Published 8 July 2026. doi:10.
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