Osteoporosis and osteoporosis therapies as determinants of implant fixation failure in arthroplasty and spinal fusion constructs: a position statement from the Fracture Working Group of the Council of Scientific Advisors of the International Osteoporosis Foundation
Methodological detailsstructured literature search, narrative synthesis
- Structured literature search
- Narrative synthesis
Recommendations
As issued by the authors
Low bone mineral density (BMD) is associated with implant fixation failure across arthroplasty and spinal fusion
In arthroplasty, RCTs show preservation of periprosthetic BMD with bisphosphonates; registry analyses suggest improved implant survival
In spinal fusion, anabolic agents show the most consistent evidence for enhanced fusion mass and earlier union
Systematic peri-operative bone health optimization may improve construct longevity
Original publication
Osteoporosis and osteoporosis therapies as determinants of implant fixation failure in arthroplasty and spinal fusion constructs: a position statement from the Fracture Working Group of the Council of Scientific Advisors of the International Osteoporosis Foundation. Osteoporos Int. Published 18 June 2026. doi:10.
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