Type 2 & other diabetes

Optimisation of care among patients with diabetes mellitus and acute coronary syndrome through a specialised cardiodiabetes service—A registry study

Diabet MedPublished Retrospective registry-based cohort study

Authors' conclusion

The introduction of a joint-speciality cardiodiabetes service improved the care and survival of patients with acute coronary syndrome and diabetes mellitus.

Study context

Population
Patients with acute coronary syndrome and DM presenting to a regional heart centre
Participants
362 vs 711
Exposure
Post-intervention vs pre-intervention
  • Post-interventionn = 362
  • Pre-interventionn = 711reference
Outcome
Proportion of patients with a valid HbA1c during admission; initiation of guideline-recommended glucose- and lipid-lowering therapies
Methodological detailsobservational, before-and-after implementation, regional heart centre
  • Observational
  • Before-and-after implementation
  • Regional heart centre

Main finding

As reported in the abstract

Valid HbA1c measurement at baseline · median follow-up 29.7 months

P = 0.043

Observational data: associations, not effects.

Further findings

Prescribed SGLT2 inhibitors

events/100 patient-years

OutcomePost-interventionPre-interventionRR (95% CI)P value
All-cause mortality5.212.30.42 (0.28–0.61)P < 0.001

Safety

OutcomePost-interventionPre-interventionRR (CI)P value
First events of acute kidney injury10.013.00.77 (0.57–1.03)P = 0.090
All events of acute kidney injury16.622.10.75 (0.60–0.94)P = 0.015

Original publication

Optimisation of care among patients with diabetes mellitus and acute coronary syndrome through a specialised cardiodiabetes service—A registry study. Diabet Med. Published 2 April 2025. doi:10.1111/dme.70030

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