Novel pathological implications of serum uric acid with cardiovascular disease risk in obesity
Authors' conclusion
SUA is an effective predictor of CVD events in female obese patients and a risk factor for CVD incident in obese patients.
Study context
- Population
- Obese Japanese outpatients, Japan Obesity and Metabolic Syndrome Study335 followed to year 5
- Participants
- 450 outpatients
- Exposure
- Hyperuricemia vs normal serum uric acid (SUA)
- Outcome
- Occurrence of macrovascular complications (CVD events) in relation to SUA levels
- Follow-up
- 5 years
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
CVD events
CVD incidence rate
15.8 per 1000 person-years
Patients with CVD events (15 coronary heart disease, 7 stroke, 6 arteriosclerosis obliterans events)
39
Observational data: associations, not effects.
Original publication
Novel pathological implications of serum uric acid with cardiovascular disease risk in obesity. Diabetes Res Clin Pract. Published 22 September 2023. doi:10. 1016/ j. diabres. 2023. 110919
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