Obesity

Novel pathological implications of serum uric acid with cardiovascular disease risk in obesity

Diabetes Res Clin PractPublished Prospective cohort study

Authors' conclusion

SUA is an effective predictor of CVD events in female obese patients and a risk factor for CVD incident in obese patients.

Study context

Population
Obese Japanese outpatients, Japan Obesity and Metabolic Syndrome Study335 followed to year 5
Participants
450 outpatients
Exposure
Hyperuricemia vs normal serum uric acid (SUA)
Outcome
Occurrence of macrovascular complications (CVD events) in relation to SUA levels
Follow-up
5 years
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

CVD events

CVD incidence rate

15.8 per 1000 person-years

Patients with CVD events (15 coronary heart disease, 7 stroke, 6 arteriosclerosis obliterans events)

39

Observational data: associations, not effects.

Original publication

Novel pathological implications of serum uric acid with cardiovascular disease risk in obesity. Diabetes Res Clin Pract. Published 22 September 2023. doi:10.1016/j.diabres.2023.110919

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