Non-pharmacological interventions to improve cardiovascular risk factors in people with diabetic foot disease: A systematic review and meta-analysis
Authors' conclusion
Non-pharmacological interventions show promise in improving CVD risk in diabetic foot disease.
Study context
- Population
- People with T1D or T2D and current or previous diabetic foot disease20 studies
- Comparison
- Non-pharmacological interventions
- Outcome
- Change in CVD risk factors
Methodological detailsrandom effects meta-analyses, narrative syntheses, Databases and trials registers searched from inception to December 6th 2023
- Random effects meta-analyses
- Narrative syntheses
- Databases and trials registers searched from inception to December 6th 2023
Pooled result
As reported in the abstract
CVD risk factors · post-intervention
- Significant post-intervention changes in FPG, serum insulin, insulin sensitivity and resistance, HbA1c, TG, total cholesterol, LDL-C and C-reactive protein
- No effects in very low- or HDL-C or BMI
Original publication
Non-pharmacological interventions to improve cardiovascular risk factors in people with diabetic foot disease: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 24 February 2024. doi:10. 1016/ j. diabres. 2024. 111590
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