No effect of surgery on kidney and cardiovascular risk factors in mild primary hyperparathyroidism: secondary analyses from a 10-year randomized controlled trial
Authors' conclusion
PTX does not appear to affect renal function or markers of CVD and vascular inflammation in mild PHPT in a ten-year perspective.
Study context
- Population
- Patients with mild primary hyperparathyroidism (PHPT), 8 Scandinavian referral centres (Sweden, Norway, Denmark), included 1998–2005150 analysed
- Participants
- 191 patients
- Comparison
- PTX vs observation without intervention
- PTXn = 70
- OBSn = 80reference
Methodological detailsprospective, multicentre
- Prospective
- Multicentre
Primary result
As reported in the abstract
Renal function (eGFR), markers of cardiovascular disease (CVD) and vascular/systemic inflammation · 10 years
- No differences in the development of renal function or vascular and systemic inflammation
Further findings
Bone turnover marker CTX-1 · 10 years
- CTX-1 lower with PTX after 10 years
Original publication
No effect of surgery on kidney and cardiovascular risk factors in mild primary hyperparathyroidism: secondary analyses from a 10-year randomized controlled trial. Eur J Endocrinol. Published 27 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →