Type 2 & other diabetes

New-onset diabetes mellitus post COVID-19 infection: a systematic review and meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis of cohort studies

Pooled result · NODMResult — go to the resultRelative risk 1.41 95 % CI 1.07–1.84

Authors' conclusion

COVID-19 infection is associated with a significantly higher risk of NODM. Close monitoring for hyperglycaemia should be considered following COVID-19 infection, especially in adult patients requiring hospital or ICU admission.

Study context

Population
Peer-reviewed cohort studies comparing new-onset DM (new-onset diabetes mellitus (NODM)) incidence in COVID-19 patients vs controls without COVID-19; PubMed, Medline, Embase, Scopus12 studies, >48 million
Comparison
COVID-19 vs no COVID-19
Outcome
Relative risk of new-onset DM (NODM)
Methodological detailsrandom-effects meta-analysis, subgroup analyses
  • Random-effects meta-analysis
  • Subgroup analyses

Pooled result

NODM

Relative risk

1.41

95 % CI 1.07–1.84

COVID-19vs Control
RR 1.41 (95 % CI 1.07–1.84)

As reported in the abstract

Further pooled results

Subgroups: DM type, age, COVID-19 severity

Higher incidence of T2D than T1D post COVID-19
Increased risk of NODM in adults and patients with higher disease severity

Original publication

New-onset diabetes mellitus post COVID-19 infection: a systematic review and meta-analysis. Diabetes Res Clin Pract. Published 11 August 2025. doi:10.1016/j.diabres.2025.112417

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