Thyroid disease

Neck Ultrasound in Older Adults With Thyroid Nodules: Considering Risk of Death From Other Causes

Endocr PractPublished Retrospective cohort study

Authors' conclusion

Older adults with thyroid nodules are more likely to die of causes other than thyroid cancer. Neck ultrasound for surveillance should be tailored to the patient, with consideration for comorbidities and life expectancy.

Study context

Population
Patients aged ≥ 65 with thyroid nodule(s), CMS data combined with University of Michigan Medicine data, 2016–2021; median age 75 years, 71.2% female
Participants
18,001 patients
Exposure
Patients who died of other causes vs rest of cohort
  • Died of other causesn = 2,387
Outcome
Cause of death
Follow-up
Median 2 years, range 0-6 years
Methodological detailsMedicare claims linked to single-institution health data
  • Medicare claims linked to single-institution health data

Main finding

As reported in the abstract

Died of thyroid cancer

29

0.2%

Died of other causes

2387

13.3%

Observational data: associations, not effects.

Further findings

Neck US during study period

P < 0.001

OutcomeDied of other causesRest of
Number of comorbiditiesmean 1.73 (range 0–5)— not stated in the abstract

— not stated in the abstract

Number of comorbidities — Mean comorbidities in entire cohort
1.2 (range 0-6)

Original publication

Neck Ultrasound in Older Adults With Thyroid Nodules: Considering Risk of Death From Other Causes. Endocr Pract. Published 15 July 2025. doi:10.1016/j.eprac.2025.06.007

Composed by AI from the published abstract and checked against it. How Briefs are made →

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