Modification of bone architecture following sleeve gastrectomy: a five-year follow-up
Authors' conclusion
In conclusion, the study demonstrates that SG induces not only an alteration in bone turnover and aBMD, but also a reduction in vBMD at the hip, predominantly due to trabecular component deterioration as determined by 3D-Shaper software.
Study context
- Population
- Patients with obesity undergoing sleeve gastrectomy
- Participants
- 45 patients
- Outcome
- Changes in aBMD, bone turnover markers, and trabecular and cortical vBMD after SG
- Follow-up
- 1, 2 and 5 yr
Methodological details5-yr follow-up, 3D-Shaper software at the hip
- 5-yr follow-up
- 3D-Shaper software at the hip
Main finding
As reported in the abstract
Changes in aBMD, vBMD and bone turnover markers after SG
- Femoral neck areal BMD (aBMD) change over 5 yr
- −9.7%
- Total hip aBMD change over 5 yr
- −10.7%
- Femoral neck aBMD change at 1 yr (greatest loss)
- −5.9%
- Total hip aBMD change at 1 yr (greatest loss)
- −6.3%
- Integral hip volumetric BMD (vBMD) decrease at 1, 2 and 5 yr (significant)
- 6.6%, 7.7%, 10.7%
- Trabecular vBMD decrease at 1, 2 and 5 yr
- 10.5%, 12.0%, 17.2%
- Cortical vBMD decrease at 1, 2 and 5 yr
- 1.4%, 1.9%, 2.9%
Observational data: associations, not effects.
Further findings
Mean cortical thickness and structural parameters · 1, 2 and 5 yr
- Modest decrease in mean cortical thickness at 1, 2 and 5 yr
- 2.5%, 2.8%, 3.9%
- Alteration in structural parameters
Factors associated with bone loss
- Older age and greater body weight loss most associated with increased loss of aBMD and vBMD
Original publication
Modification of bone architecture following sleeve gastrectomy: a five-year follow-up. J Bone Miner Res. Published 18 December 2024. doi:10.
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