Thyroid disease

Micro-Costing Analysis of Thyroid Radiofrequency Ablation Compared with Hemithyroidectomy in Outpatient and Inpatient Settings

ThyroidPublished Retrospective micro-costing analysis

Main finding · Cost over a one-year care cycleResult — go to the resultDifference $1628.23 lower (29.0%)

Authors' conclusion

Over one year, the base-case cost for thyroid RFA was $1628.23 lower (29.0%) than the mean cost of all hemithyroidectomies. The cost savings of thyroid RFA are driven by eliminating the need for operating room and inpatient admission resources. Nodule regrowth requiring repeat ablation or delayed surgery is a critical factor that significantly affects the overall cost of RFA.

Study context

Population
Patients with thyroid nodules treated January 2023–May 2025 at two tertiary hospitals in Toronto, Canada
Participants
42 vs 112
Exposure
Thyroid radiofrequency ablation (RFA) vs hemithyroidectomy
  • RFAn = 42
  • Hemithyroidectomyn = 112reference
Outcome
Health system costs (2025 Canadian Dollars) across a one-year patient care cycle from initial consultation to one year of follow-up
Follow-up
One year
Methodological detailsbottom-up approach, deterministic one-way sensitivity analyses, two tertiary hospitals
  • Bottom-up approach
  • Deterministic one-way sensitivity analyses
  • Two tertiary hospitals

Main finding

Cost over a one-year care cycle

Difference

$1628.23 lower (29.0%)

By group

RFA

$3985.05

base-case

Hemithyroidectomy

$5613.28

mean

As reported in the abstract

Observational data: associations, not effects.

Further findings

Sensitivity analysis: cost equivalence of RFA vs outpatient hemithyroidectomy

Patients requiring delayed surgery
13.3%
Patients requiring repeat RFA
18.7%

Sensitivity analysis: cost equivalence of RFA vs inpatient hemithyroidectomy

Patients requiring delayed surgery
31.3%
Patients requiring repeat RFA
44.0%

Original publication

Micro-Costing Analysis of Thyroid Radiofrequency Ablation Compared with Hemithyroidectomy in Outpatient and Inpatient Settings. Thyroid. Published 1 August 2026. doi:10.1177/10507256261474364

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