Mediating Effects of Technology-Based Therapy on the Relationship Between Socioeconomic Status and Glycemic Management in Pediatric Type 1 Diabetes
Main finding · HbA1c, Q5 vs Q1, and mediation by technology useResult — go to the resultDifference +1.17 %Authors' conclusion
CSII and rtCGM use partially mediated the significant discrepancies observed with SES and glycemic management
Study context
- Population
- Children aged 0–18 years with T1D and valid postal codes, 2018–2020, single centre; census-based material deprivation (MD) quintiles
- Participants
- 813 children
- Exposure
- Most (Q5) vs least (Q1) deprived MD quintile; mediation by CSII, Real-time CGM (rtCGM) and intermittently scanned CGM (isCGM) use
- Outcome
- Glycemic management (HbA1c)
Methodological detailssingle-centre, mediation analysis
- Single-centre
- Mediation analysis
Main finding
HbA1c, Q5 vs Q1, and mediation by technology use
Difference
+1.17 %
P < 0.0001
As reported in the abstract
- Indirect effect of rtCGM use on Q1–Q5 HbA1c difference (P < 0.0001); 12.0% of difference
- 0.14%
- Indirect effect of CSII use on Q1–Q5 HbA1c difference (P < 0.0001); 23.1% of difference
- 0.25%
Observational data: associations, not effects.
Further findings
Technology use
- CGM users
- 379 (46.6%)
- CSII users
- 246 (30.3%)
- rtCGM and CSII associated with both MD and HbA1c; isCGM not
Original publication
Mediating Effects of Technology-Based Therapy on the Relationship Between Socioeconomic Status and Glycemic Management in Pediatric Type 1 Diabetes. Diabetes Technol Ther. Published 5 December 2022. doi:10.
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