Type 2 & other diabetes

Long-term Weight Training and Mortality in U.S. Male Health Professionals With and Without Type 2 Diabetes

Diabetes CarePublished Prospective cohort study

Authors' conclusion

A moderate level of long-term weight training was associated with lower mortality, independently of aerobic activity, among male health professionals with and without type 2 diabetes. Addition of weight training to aerobic activities may provide further benefit in mortality risk reduction. Studies are required to confirm our findings in diverse populations.

Study context

Population
Men without T2D (n 31,140) and with T2D (n 2,588), Health Professionals Follow-up Study (1992–2018)12,607 deaths
Exposure
Long-term weight training vs no weight training
Outcome
Mortality
Follow-up
Up to 26 years
Methodological detailsrepeated biennial questionnaire assessment, adjusted for aerobic activity
  • Repeated biennial questionnaire assessment
  • Adjusted for aerobic activity

Main finding

As reported in the abstract

Mortality, men without T2D · up to 26 years
Each group vs no weight trainingHazard ratio (95% CI)P value
1-59 min/week14% lower mortality; adjusted for aerobic activity
0.86(0.82–0.89)
60-149 min/week8% lower mortality; adjusted for aerobic activity
0.92(0.85–0.99)
≥150 min/weeknot significantly associated
1.05(0.91–1.20)
overall P trend = 0.94; P quadratic < 0.001

Observational data: associations, not effects.

Further findings

Meeting aerobic guideline (≥150 min/week) plus any weight training

Lower mortality
20-34%

Mortality, men with T2D

Deaths among men with T2D
988
Moderate pre-diagnosis weight training associated with lower mortality; post-diagnosis weight training showed no association
Both weight training and aerobic activity before and after diagnosis associated with lower mortality

Original publication

Long-term Weight Training and Mortality in U.S. Male Health Professionals With and Without Type 2 Diabetes. Diabetes Care. Published 21 November 2022. doi:10.2337/dc21-2420

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