Long-term weight change, incident cardiovascular disease and all-cause mortality among diabetic adults
Authors' conclusion
Our findings indicated that the risk for incident CVD and all-cause mortality was potentially reinforced in diabetic adults who were obese at age 25 but non-obese at midlife and who remained stable obese vis-à-vis those with stable non-obesity.
Study context
- Population
- US diabetic adults aged 40–79 years, non-pregnant, with self-reported weight at age 25 and 10 years before baseline, National Health and Nutrition Examination Survey (NHANES) 1988–2018
- Exposure
- Weight change patterns from young (age 25) to middle adulthood vs stable non-obesity
- Outcome
- Incident CVD and all-cause mortality
Main finding
As reported in the abstract
Incident CVD · over following 10 years
Cardiovascular disease (CVD) cases averted if total population had maintained non-obese from young to middle adulthood
12 %
Observational data: associations, not effects.
Further findings
All-cause mortality
- Increased risk with stable-obesity vs stable non-obesity
Original publication
Long-term weight change, incident cardiovascular disease and all-cause mortality among diabetic adults. Diabetes Res Clin Pract. Published 2 December 2024. doi:10. 1016/ j. diabres. 2024. 111946
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