Long Term Outcomes in Patients With Differences in Sex Development in Lucknow, India
Authors' conclusion
The absence of prominent gender dysphoria in our young adults was noteworthy, as was their preference for early genital surgery. Lack of adequate mental health support is a high alert for our teams involved in the care of DSD and as well as for policy-makers.
Study context
- Population
- Young adults with a difference in sex development (DSD), Lucknow, India; median (IQR) age 23 (19–27) years; 16 raised male, 15 female31 young adults with DSD
- Participants
- 31 / 46 / 43
- Exposure
- DSD vs Healthy controls vs T1D
- DSDn = 31
- Healthy controlsn = 46reference
- T1Dn = 43reference
- Outcome
- Gender identity, opinion on genital surgery timing, suicidality, romantic/sexual life
Main finding
As reported in the abstract
- Gender identity identical with sex of rearing
- 30
- Thought genital surgery should be in childhood
- 27
- Attempted suicide at least once
- Six of 31
- Reported past sexual abuse
- Four
- Reported romantic relationships
- Twelve
- Reported sexual intercourse
- seven
- Aversion to and fear of sexual activity, due to fear of rejection
- Eleven of 31
- Heterosexual orientation
- 25 of 29
Observational data: associations, not effects.
Further findings
Quality of life (QOL) (SF36)
- QOL scores not different between patients and healthy controls or people with T1D
Mental QOL score by history of teasing
- With vs without history of teasing
- 37.10 ± 16.01 vs. 47.76 ± 9.4, p = 0.04
- Lower with history of teasing
Mental QOL score by suicidal thoughts
- With vs without suicidal thoughts
- 33.9 ± 14.51 vs. 45.65 ± 13.2, p = 0.04
- Lower with suicidal thoughts
Original publication
Long Term Outcomes in Patients With Differences in Sex Development in Lucknow, India. Clin Endocrinol (Oxf). Published 11 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →