Long‐term cancer outcomes after bariatric surgery
Main finding · Any cancer incidenceResult — go to the resultHazard ratio 0.75 95% CI 0.69–0.81Authors' conclusion
Bariatric surgery was associated with lower all-cancer and obesity-related cancer incidence among female patients. Cancer mortality was significantly lower among females in the surgical group versus the nonsurgical group.
Study context
- Population
- Bariatric surgery patients (surgery 1982–2018) and matched nonsurgical comparison group; follow-up 1982–2019matched 1:1
- Exposure
- Bariatric surgery vs nonsurgical comparison group
- Bariatric surgeryn = 21,837
- Outcome
- Cancer incidence and mortality, stratified by obesity- and non-obesity-related cancers, sex, cancer stage, and procedure
Methodological detailsmatched 1:1 by age, sex, and BMI
- Matched 1:1 by age, sex, and BMI
Main finding
Any cancer incidence
Hazard ratio
0.75
95% CI 0.69–0.81
P < 0.001
Bariatric surgeryvs Nonsurgical comparison
HR 0.75 (95% CI 0.69–0.81); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | P value | |
|---|---|---|---|
| Any cancer incidence, by sexFemale surgeryvs NonsurgicalFemales | 0.67 (0.62–0.74) | P < 0.001 | |
| Obesity-related cancers (breast, ovarian, uterine, colon), femalesFemale surgeryvs Nonsurgical females41% lower risk | 0.59 (0.52–0.66) | P < 0.001 | |
| 0.512Hazard ratio (log scale) |
Cancer mortality, females
| HR (95% CI) | P value | ||
|---|---|---|---|
| Females after surgerySignificantly lower after surgery in females | 0.53 (0.44–0.64) | P < 0.001 | |
| 0.512Hazard ratio (log scale) |
- Any cancer incidence, by sex — HR lower for females than for males
- p < 0.001
Any cancer incidence, by sex
- Not lower among male surgery patients
Original publication
Long‐term cancer outcomes after bariatric surgery. Obesity (Silver Spring). Published 22 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →