Lifestyle Intervention With Smartphone App and isCGM for People at High Risk of Type 2 Diabetes: Randomized Trial
Authors' conclusion
Intervention with a smartphone app and intermittently scanned continuous glucose monitoring increased glycemic control accompanied by decreased carbohydrate intake and weight loss. Further trials are needed to confirm whether these interventions can reduce incident type 2 diabetes.
Study context
- Population
- People at high risk of T2D: HbA1c 5.6% to 6.4% or fasting blood glucose 110 to 125 mg/dL, and body mass index (BMI) >23 kg/m² but <40 kg/m²; mean age 48.1 years, mean BMI 26.6 kg/m², 80.4% male
- Participants
- 168 people
- Comparison
- Lifestyle coaching via smartphone app plus isCGM vs control
- Appn = 82
- Cn = 86reference
- Primary endpoint
- Between-group difference in change in TIR of blood glucose 70–140 mg/dL (3.9-7.8 mmol/L) from before to after the study period
- Follow-up
- 12 weeks
Methodological detailsunblinded, 12-week, offline recruitment
- Unblinded
- 12-week
- Offline recruitment
Primary result
As reported in the abstract
TIR 70–140 mg/dL
- App vs C: P = 0.03
Further findings
| Outcome | P value |
|---|---|
| Change in TBR (blood glucose <70 mg/dL) · 12 weeksImproved in App | P = 0.02 |
| Change in BMI · 12 weeksReduced in App vs C | P = 0.017 |
Change in TAR · 12 weeks
- Changes in TAR did not differ
Original publication
Lifestyle Intervention With Smartphone App and isCGM for People at High Risk of Type 2 Diabetes: Randomized Trial. J Clin Endocrinol Metab. Published 1 November 2023. doi:10.
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