Leisure-time physical activity and sedentary behavior trajectories during middle and late adulthood in relation to type 2 diabetes mellitus: An 11-year longitudinal study
Authors' conclusion
This prospective study suggests that maintaining higher levels of LTPA and lower levels of LTSB may reduce the risk of T2DM during middle and late adulthood.
Study context
- Population
- Participants of the China Health and Nutrition Survey (CHNS), aged 31 to 77 years in 2004, followed to 2015
- Participants
- 7,188 participants
- Exposure
- Long-term trajectories of leisure-time physical activity (LTPA) and leisure-time sedentary behavior (LTSB)
- Outcome
- New-onset T2D
- Follow-up
- Mean 9.13 years
Methodological detailsgroup-based trajectory modeling, Cox regression
- Group-based trajectory modeling
- Cox regression
Main finding
As reported in the abstract
T2D risk
Hazard ratio (95% CI)
LTPA high decreasingvs LTPA inactive stable
0.55(0.30–0.99)
LTSB high increasingvs LTSB low stable
2.30(1.03–5.10)
- New-onset T2D cases
- 715
- Distinct trajectories identified for each of LTPA and LTSB
- 3
Observational data: associations, not effects.
Original publication
Leisure-time physical activity and sedentary behavior trajectories during middle and late adulthood in relation to type 2 diabetes mellitus: An 11-year longitudinal study. Diabetes Res Clin Pract. Published 3 February 2026. doi:10.
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