Osteoporosis, bone & mineral

Introduction of an order set after hip fracture improves osteoporosis medication initiation and persistence: a population-based before-after analysis

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

Introduction of a hip fracture OS significantly increased AOM initiation and persistence at 1-year post-fracture. There was no significant difference in secondary fractures.

Study context

Population
Individuals 50+ years with surgical treatment for low-energy hip fracture, 2010–2019, Manitoba, Canada
Participants
2,150 vs 813
Exposure
Hip fracture order set vs control hospitals without order set (OS)
  • Controln = 2,150reference
  • OSn = 813
Outcome
Anti-osteoporosis medication (AOM) initiation after fracture, OS group year before vs year after OS introduction
Methodological detailspopulation-based, before-after analysis, linked administrative health data
  • Population-based
  • Before-after analysis
  • Linked administrative health data

Main finding

As reported in the abstract

P < 0.001

Observational data: associations, not effects.

Further findings

Secondary fractures

P = 0.38

OutcomeP value
Persistence on AOM, OS group year before vs year afterP < 0.001
  • Persistence on anti-osteoporosis medication (AOM), OS group year before vs year after: OS, year before 17.7%
  • Persistence on AOM, OS group year before vs year after: OS, year after 28.4%

Original publication

Introduction of an order set after hip fracture improves osteoporosis medication initiation and persistence: a population-based before-after analysis. Osteoporos Int. Published 5 June 2024. doi:10.1007/s00198-024-07131-3

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