Innovative Approaches to Improve the Success of Pituitary Surgery in Cushing's Disease: A Cost‐Effectiveness Perspective
Authors' conclusion
Our early health economic model exploring the conditions for success of innovations in pituitary surgery shows room for improvement, but also the importance of accurate health-related quality of life data to assess the economic value of innovations in individuals with CD.
Study context
- Population
- Simulated patients with CD and pituitary surgery as primary treatment; model input from literature and expert opinion
- Comparison
- Innovations in pituitary surgery vs current pituitary surgery
- Outcome
- Incremental healthcare costs and incremental QALYs
- Follow-up
- 10 years
Methodological detailsearly health economic modelling study, decision tree and state-transition model, 10-year time horizon, headroom and threshold analysis, probabilistic and one-way sensitivity analyses
- Early health economic modelling study
- Decision tree and state-transition model
- 10-year time horizon
- Headroom and threshold analysis
- Probabilistic and one-way sensitivity analyses
Main finding
As reported in the abstract
Headroom analysis per patient
Quality-adjusted life-years (QALYs) that could be gained per patient
0.028
Euros that could be saved per patient
2082
Maximum innovation price for cost-effectiveness at willingness to pay of 80,000 euros
4288 euros
95% CI 3377–5181
Further findings
Sensitivity analyses
- Utility values mainly determined cost-effectiveness
Original publication
Innovative Approaches to Improve the Success of Pituitary Surgery in Cushing's Disease: A Cost‐Effectiveness Perspective. Clin Endocrinol (Oxf). Published 5 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →