Influence of metabolic syndrome and lifestyle factors on thyroid nodules in Chinese adult men: a cross-sectional study
Authors' conclusion
The prevalence of thyroid nodules in Chinese adult males is relatively moderate to low. The factors identified in this study can help clinicians identify high-risk patients and develop targeted screening strategies for the timely detection of thyroid nodules. However, further mechanistic research and longitudinal studies are necessary to explore the underlying causes and establish causal relationships.
Study context
- Population
- Adult men undergoing medical examination at a general hospital in southern China, 2015–2020
- Participants
- 183,990 men
- Outcome
- Thyroid nodules and their relationship with metabolic syndrome and lifestyle factors
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Prevalence of thyroid nodules among Chinese adult males
14.9%
Observational data: associations, not effects.
Further findings
Factors associated with thyroid nodules (multivariate logistic regression)
- Risk factors: advanced age, irregular meal time, smoking or quitting smoking, quitting drinking, heavy manual labor, hypertension, diabetes, dyslipidemia and centripetal obesity
- Protective factors: ethnic minority and drinking alcohol
Structural equation modeling
- Metabolic syndrome mediated lifestyle influences on thyroid nodules
Original publication
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