Type 2 & other diabetes

Influence of neighborhood-level socioeconomic deprivation and individual socioeconomic position on risk of developing type 2 diabetes in older men: a longitudinal analysis in the British Regional Heart Study cohort

BMJ Open Diabetes Res CarePublished Prospective cohort study

Main finding · Incident T2D (368 cases)Result — go to the resultAge-adjusted HR 2.45 95% CI 1.36–4.42

Authors' conclusion

Inequalities in T2DM risk persist in later life, both in relation to neighborhood-level and individual-level socioeconomic factors. Underlying modifiable risk factors continue to need to be addressed in deprived older age populations to reduce disease burden.

Study context

Population
Men aged 60–79 years in 1998–2000, British Regional Heart Study; prevalent T2D excluded3,706 analysed
Participants
4,252 men
Exposure
Neighborhood-level deprivation (IMD quintiles) and individual socioeconomic position (SEP) (social class) in relation to incident T2D
Outcome
Incident T2D, ascertained from primary care records
Follow-up
18 years
Methodological detailslongitudinal, population-based (British Regional Heart Study), Cox proportional hazard models
  • Longitudinal
  • Population-based (British Regional Heart Study)
  • Cox proportional hazard models

Main finding

Incident T2D (368 cases)

Age-adjusted HR

2.45

95% CI 1.36–4.42

P = 0.001

Social class Vvs Social class I
age-adjusted HR 2.45 (95% CI 1.36–4.42); P = 0.001

As reported in the abstract

Age-adjusted HR per IMD quintile increase (least to most deprived), 95% CI 1.06 to 1.23, p=0.0005
1.14

Observational data: associations, not effects.

Further findings

Cumulative individual adverse socioeconomic factors score

HR per point increase, 95% CI 1.05 to 1.24
1.14

Original publication

Influence of neighborhood-level socioeconomic deprivation and individual socioeconomic position on risk of developing type 2 diabetes in older men: a longitudinal analysis in the British Regional Heart Study cohort. BMJ Open Diabetes Res Care. Published 31 October 2023. doi:10.1136/bmjdrc-2023-003559

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