Influence of neighborhood-level socioeconomic deprivation and individual socioeconomic position on risk of developing type 2 diabetes in older men: a longitudinal analysis in the British Regional Heart Study cohort
Main finding · Incident T2D (368 cases)Result — go to the resultAge-adjusted HR 2.45 95% CI 1.36–4.42Authors' conclusion
Inequalities in T2DM risk persist in later life, both in relation to neighborhood-level and individual-level socioeconomic factors. Underlying modifiable risk factors continue to need to be addressed in deprived older age populations to reduce disease burden.
Study context
- Population
- Men aged 60–79 years in 1998–2000, British Regional Heart Study; prevalent T2D excluded3,706 analysed
- Participants
- 4,252 men
- Exposure
- Neighborhood-level deprivation (IMD quintiles) and individual socioeconomic position (SEP) (social class) in relation to incident T2D
- Outcome
- Incident T2D, ascertained from primary care records
- Follow-up
- 18 years
Methodological detailslongitudinal, population-based (British Regional Heart Study), Cox proportional hazard models
- Longitudinal
- Population-based (British Regional Heart Study)
- Cox proportional hazard models
Main finding
Incident T2D (368 cases)
Age-adjusted HR
2.45
95% CI 1.36–4.42
P = 0.001
Social class Vvs Social class I
age-adjusted HR 2.45 (95% CI 1.36–4.42); P = 0.001
As reported in the abstract
- Age-adjusted HR per IMD quintile increase (least to most deprived), 95% CI 1.06 to 1.23, p=0.0005
- 1.14
Observational data: associations, not effects.
Further findings
Cumulative individual adverse socioeconomic factors score
- HR per point increase, 95% CI 1.05 to 1.24
- 1.14
Original publication
Influence of neighborhood-level socioeconomic deprivation and individual socioeconomic position on risk of developing type 2 diabetes in older men: a longitudinal analysis in the British Regional Heart Study cohort. BMJ Open Diabetes Res Care. Published 31 October 2023. doi:10. 1136/ bmjdrc-2023-003559
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