Thyroid disease

Increased workload without clinical benefit: Results following implementation of the ACR‐TIRADS system for thyroid nodules

Clin Endocrinol (Oxf)Published Audit

Authors' conclusion

ACR-TIRADS introduction increased workload (FNAs and operations), without increasing the proportion of cancers/FNA. It led to a few more cancers being diagnosed, but many were small and of uncertain clinical significance.

Study context

Population
Individuals undergoing thyroid fine needle aspiration (FNA) 2017–2019 at a large public hospital in Auckland, New Zealand
Participants
422 individuals564 FNAs
Comparison
Post-TIRADS vs pre-TIRADS
Outcome
Proportion of cancers/FNA
Methodological detailsbefore/after study, single-centre, before/after ACR-TIRADS
  • Before/after study
  • Single-centre
  • Before/after ACR-TIRADS

Main finding

As reported in the abstract

Further findings

FNA results B5-B6

FNA results B5-B6 — FNAs needed to identify an additional B5/B6 lesion
15

Workload after ACR-TIRADS introduction

FNA recommendations increased
greater than twofold
FNAs performed increased
71%-83%
Monthly rate of FNAs increased
60%
Monthly rate of operations increased
40%

FNA results B5-B6

B2-B4 proportions remained stable

Cytology by TIRADS level (B5/B6; B2)

TIRADS-5: B5/B6; B2
20%; 30%
TIRADS-3: B5/B6; B2
2%; 57%
TIRADS-4: B5/B6; B2
9%; 56%

Cancer diagnoses

Cancer in primary nodule
54 (13%)
Papillary thyroid carcinoma
37/54 (69%)
Additional cancers diagnosed per year
About 5
Small cancers <2 cm (post vs pre)
49% vs. 8%
Small cancers <1 cm (post vs pre)
17% vs. 0%

Original publication

Increased workload without clinical benefit: Results following implementation of the ACR‐TIRADS system for thyroid nodules. Clin Endocrinol (Oxf). Published 5 February 2023. doi:10.1111/cen.14883

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