Increased fall risk in people with type 2 diabetes and cardiovascular disease: a systematic review and meta-analysis
Pooled result · FallsResult — go to the resultPooled odds ratio 1.29 95% CI 1.03–1.63Authors' conclusion
This review and meta-analysis found an increased fall risk in people with T2D and coexisting CVD; however, current evidence remains insufficient to establish a definitive causal relationship between CVD and fall risk, despite the observed higher fall prevalence.
Study context
- Population
- People with T2D, with or without cardiovascular disease (CVD); studies from PubMed, Embase and Cochrane
- Comparison
- T2D with coexisting CVD vs T2D without CVD
- Outcome
- Risk of falls
Methodological detailsPRISMA guidelines, quality assessment with JADAD, NOS and GRADE
- PRISMA guidelines
- Quality assessment with JADAD, NOS and GRADE
Pooled result
Falls
Pooled odds ratio
1.29
95% CI 1.03–1.63
T2D + CVDvs T2D without CVD
pooled OR 1.29 (95% CI 1.03–1.63)
As reported in the abstract
Further pooled results
Specific CV conditions (hypertension, orthostatic hypotension, HF, AF, ischemic disease) and fall risk
- Clear associations with fall risk remained inconclusive
Autonomic dysfunction, postural instability and blood pressure dysregulation
- Some studies indicated a contribution to fall risk, but findings were inconsistent
Original publication
Increased fall risk in people with type 2 diabetes and cardiovascular disease: a systematic review and meta-analysis. Osteoporos Int. Published 24 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →