Incidence and predictors of residual back pain after percutaneous vertebral augmentation in osteoporotic vertebral compression fracture: a systematic review and meta analysis
Authors' conclusion
Fifteen risk factors and two protective factors for RBP were identified.
Study context
- Population
- Patients with osteoporotic vertebral compression fractures (OVCFs) after percutaneous vertebral augmentation (PVA)
- Participants
- 8,806 patients27 studies
- Outcome
- Incidence of residual back pain (RBP) after PVA
Methodological detailsmeta-regression, subgroup analyses, sensitivity analyses, Four English and three Chinese databases searched from inception until June 1, 2024
- Meta-regression
- Subgroup analyses
- Sensitivity analyses
- Four English and three Chinese databases searched from inception until June 1, 2024
Pooled result
As reported in the abstract
Incidence of RBP after PVA
Pooled incidence of residual back pain (RBP)
24.4%
95% CI 19.5–29.3%
Further pooled results
Predictors of RBP
- Predictors identified
- 17
- Risk factors
- 15
- Protective factors
- 2
- Low preoperative bone density (most frequent predictor), OR
- 2.208 (95% CI: 2.018-2.415, p < 0.001)
- Thoracolumbar fascia injury, OR
- 3.875 (95% CI: 2.752-5.457, p < 0.001)
- Maldistribution of bone cement, OR
- 2.065 (95% CI: 1.728-2.467, p < 0.001)
Original publication
Incidence and predictors of residual back pain after percutaneous vertebral augmentation in osteoporotic vertebral compression fracture: a systematic review and meta analysis. Osteoporos Int. Published 23 July 2025. doi:10.
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