Incidence of type 1 diabetes in Sardinian children aged 0–14 years has almost doubled in the last twenty years. On top of the world
Authors' conclusion
The incidence of T1D in Sardinia, unlike in other countries such as Finland, has almost doubled in the last 20 years, and currently, it appears to be the highest in the world.
Study context
- Population
- New-onset T1D patients aged 0–14 years, residents of Sardinia, 2019–2022new T1D diagnoses
- Participants
- 512 patients
- Outcome
- Incidence rate of T1D and temporal trend in standardized IR from 1989-1999
- Follow-up
- 2019-2022
Methodological detailsregistry data from all pediatric diabetology clinics, direct standardization, Poisson regression for temporal trend
- Registry data from all pediatric diabetology clinics
- Direct standardization
- Poisson regression for temporal trend
Main finding
As reported in the abstract
T1D incidence
Overall incidence rate (IR) per 100,000 person-years
73.9
95 % CI 67.6–80.0
Standardized IR (SIR) annual increase since 1989
2.3 %
CI 1.7–2.8p < 0.0001
Observational data: associations, not effects.
Further findings
DKA at onset · 2019-2022
- Frequency of DKA at onset
- 26.4 %
- No significant differences among the four years
Original publication
Incidence of type 1 diabetes in Sardinian children aged 0–14 years has almost doubled in the last twenty years. On top of the world. Diabetes Res Clin Pract. Published 15 June 2024. doi:10.
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